PH 101
Pharmaceutical Grade High Compactibility Direct Compression
High-purity microcrystalline cellulose designed for pharmaceutical formulations where compactibility, binding performance and tablet mechanical strength are essential.
Precision cellulose
for stronger formulations.
101
Microcrystalline Cellulose PH 101 is a high-purity pharmaceutical-grade excipient derived from purified cellulose.
It is widely used in solid oral dosage formulations as a multifunctional diluent and binder, particularly where good compactibility and tablet mechanical strength are required.
PH 101 is characterized by a relatively fine particle-size distribution and excellent compactibility. Its particle structure provides a high surface area for interparticle contact during compression, supporting effective particle bonding and the formation of strong, coherent tablets.
PH 101 is particularly suitable for direct-compression formulations and can also be used in other tablet manufacturing processes depending on the overall formulation design.
Engineered for
performance.
Fine Particle
Distribution
Relatively fine particles provide substantial surface area and particle-to-particle contact.
Excellent
Compactibility
Supports strong interparticle bonding during compression and tablet formation.
Effective
Binding
Contributes to tablet strength, structural integrity and resistance to mechanical stress.
Stable
Performance
White, odorless and chemically stable powder suitable for solid oral dosage formulations.
One excipient.
Multiple functions.
Excellent Compactibility
PH 101 exhibits excellent compactibility under compression. The relatively fine particles provide substantial contact between particles, facilitating the formation of strong interparticle bonds.
Effective Binding Function
Microcrystalline Cellulose PH 101 provides effective binding functionality and can contribute significantly to tablet strength and integrity.
Formulation Flexibility
PH 101 can be used as a pharmaceutical diluent or filler to provide bulk and improve the physical structure of solid dosage formulations.
Reliable Compression Performance
The relatively fine particle size and favorable deformation characteristics support efficient compaction during tablet compression.
Built for
solid dosage forms.
PH 101 can be incorporated into a variety of pharmaceutical formulations where compactibility, binding and mechanical integrity are important.
Strong bonds.
Reliable tablets.
PH 101 is particularly suitable for direct-compression applications where good compactibility and binding performance are required.
During compression, the particles form strong interparticle bonds, helping produce tablets with good mechanical integrity.
The suitability of PH 101 for a specific formulation depends on the API characteristics, excipient combination, compression force, tooling and manufacturing process.
Surface area
matters.
The relatively fine particle-size distribution of PH 101 contributes to its high surface area and favorable particle-to-particle contact during compression.
Designed around
tablet integrity.
HARDNESS
INTEGRITY
STRESS RESISTANCE
FORMATION
Final tablet hardness, friability, disintegration and dissolution are formulation-dependent properties and should be established through appropriate development and testing.
When PH 101
makes sense.
High compactibility
Effective binding
Strong tablet structure
Fine-particle MCC characteristics
Reliable compression behavior
Good mechanical integrity
Quality built
into every specification.
For pharmaceutical applications, Microcrystalline Cellulose PH 101 should comply with the applicable pharmaceutical specification and relevant pharmacopoeial or customer requirements.
Protect the
material integrity.
Store in tightly closed packaging in a clean, dry and well-ventilated environment.
Specific storage conditions, shelf life and packaging requirements should be defined according to the approved product specification and technical documentation.