PRODUCTS / CELLULOSE / PH 102
MICROCRYSTALLINE CELLULOSE

PH 102

Pharmaceutical Grade Improved Flowability Direct Compression

High-purity microcrystalline cellulose designed for pharmaceutical formulations where powder flow, die filling, compactibility and production consistency are important.

Microcrystalline Cellulose PH 102
PHARMACEUTICAL GRADE MICROCRYSTALLINE
CELLULOSE
GRADE PH 102
01 PHARMACEUTICAL GRADE
02 IMPROVED POWDER FLOW
03 GOOD COMPACTIBILITY
04 DIRECT COMPRESSION
01 / PRODUCT OVERVIEW

Designed for
better powder handling.

PH
102

Microcrystalline Cellulose PH 102 is a high-purity pharmaceutical-grade excipient derived from purified cellulose and widely used in solid oral dosage formulations.

Compared with finer-particle MCC grades such as PH 101, PH 102 has a relatively coarser particle-size distribution. This physical characteristic generally provides improved powder-flow properties while retaining the characteristic compressibility and binding functionality of Microcrystalline Cellulose.

PH 102 is particularly useful in pharmaceutical manufacturing processes where powder handling, flowability, die filling and production consistency are important considerations.

02 / KEY CHARACTERISTICS

Engineered for
efficient processing.

01

Pharmaceutical
Grade

High-purity Microcrystalline Cellulose suitable for pharmaceutical applications.

02

Coarser Particle
Distribution

Relatively coarse particles can support favorable powder-handling behavior.

03

Improved Powder
Flow

Generally improved flowability compared with finer MCC grades such as PH 101.

04

Reliable
Compression

Good to excellent compactibility with effective binding functionality.

Suitable for direct compression
Favorable powder-handling characteristics
Suitable for high-throughput tablet manufacturing
White, odorless and chemically stable powder
03 / FUNCTIONAL PROPERTIES

One excipient.
Multiple advantages.

01
POWDER FLOW

Improved Powder Flow

The relatively larger particle size of PH 102 generally provides improved powder-flow characteristics compared with finer MCC grades. Improved flow can facilitate powder movement through feeders and hoppers and support more consistent die filling during tablet manufacturing.

02
COMPRESSION

Compressibility

PH 102 retains the characteristic compressibility of Microcrystalline Cellulose and can form strong, coherent tablets under appropriate compression conditions.

03
BINDING

Binding Function

PH 102 provides effective binding functionality and can contribute to tablet mechanical integrity when incorporated appropriately into a formulation.

04
DILUENT / FILLER

Diluent / Filler Function

PH 102 can function as a multifunctional diluent and filler in solid oral dosage formulations, providing both bulk and functional compression properties.

04 / PHARMACEUTICAL APPLICATIONS

Built for
modern production.

Microcrystalline Cellulose PH 102 can be used across solid oral dosage manufacturing where powder flow and compactibility need to work together.

01 Direct-Compression Tablets
02 Immediate-Release Tablets
03 Conventional Compressed Tablets
04 Capsule Formulations
05 High-Throughput Tablet Manufacturing
06 Solid Oral Dosage Formulations
07 Improved Powder-Flow Formulations
08 Flowability / Compactibility Balance
05 / DIRECT COMPRESSION

Better flow.
Reliable compression.

PH 102 is widely suitable for direct-compression applications because its relatively coarse particle structure can provide favorable powder-flow characteristics while maintaining good compressibility.

Improved powder flow can support more consistent die filling and powder feeding, which are important considerations in high-speed tablet production.

FORMULATION NOTE

The final suitability of PH 102 depends on the complete formulation, including API properties, other excipients, compression parameters, tooling and manufacturing equipment.

06 / PARTICLE SIZE & ITS IMPORTANCE

Particle structure
matters.

The particle-size distribution of PH 102 is generally coarser than that of PH 101. This characteristic can influence powder flow, die filling, powder feeding, handling characteristics, processing efficiency and manufacturing consistency.

01 Powder flow
02 Die filling
03 Powder feeding
04 Handling characteristics
05 Processing efficiency
06 Manufacturing consistency
IMPORTANT

Particle size should not be evaluated independently. Powder flow and compression behavior can also be influenced by particle morphology, moisture content, bulk density, formulation composition and processing conditions.

07 / TABLET MANUFACTURING PERFORMANCE

Built for
consistent production.

01 CONSISTENT
POWDER FEEDING
02 IMPROVED
DIE FILLING
03 UNIFORM
TABLET WEIGHT
04 EFFICIENT
HIGH-SPEED PROCESSING
05 GOOD
COMPACTIBILITY
06 ADEQUATE
MECHANICAL STRENGTH

Actual tablet weight variation, hardness, friability, disintegration and dissolution depend on the complete formulation and manufacturing process.

08 / HIGH-SPEED MANUFACTURING

Flow that supports
production efficiency.

A key advantage of PH 102 is its favorable flow behavior in manufacturing environments where efficient powder handling is important.

Its relatively coarse particle structure can facilitate powder movement through manufacturing equipment and support consistent die filling during high-speed compression.

This makes PH 102 a practical choice for large-scale tablet manufacturing where powder flow and processing efficiency are important formulation considerations.

09 / FORMULATION CONSIDERATIONS

When PH 102
makes sense.

01

Improved powder flow

02

Reliable powder feeding

03

Consistent die filling

04

Direct-compression capability

05

Balance between flowability and compactibility

06

Efficient high-throughput manufacturing

10 / QUALITY & REGULATORY

Quality built
into every specification.

For pharmaceutical applications, Microcrystalline Cellulose PH 102 should comply with the applicable pharmaceutical specification and relevant pharmacopoeial or customer requirements.

Identification
Cellulose Content / Assay
Loss on Drying
Residue on Ignition
pH
Water-Soluble Substances
Ether-Soluble Substances
Elemental Impurities, where applicable
Microbial Quality
Particle-Size Distribution
Bulk Density
Other Customer-Specific Requirements
SPECIFICATION

The final product specification should be established according to the applicable pharmacopoeial requirements and the manufacturer's approved technical specification.

11 / STORAGE & HANDLING

Protect the
material integrity.

Store in tightly closed packaging in a clean, dry and well-ventilated environment.

Clean environment Dry conditions Controlled handling Protected from contamination Protected from direct sunlight Protected from excessive moisture

Specific storage conditions, shelf life and packaging requirements should be defined according to the approved product specification and technical documentation.